Year 11 | 23 April 2019 | firstname.lastname@example.org
Moderate wine consumption is associated with lower hemostatic and inflammatory risk in women. Although white wines are generally low in polyphenol content as compared to red wines, Champagne wine has been shown to contain relatively high amounts of phenolic acids
Moderate wine consumption has been associated with reduced cardiovascular (CV) risk, but most investigations have been conducted in Caucasian populations.
To investigate the relationship of wine consumption to CV risk markers, Chicago resarchers studied a multi-ethnic sample of middle-aged, healthy women (N= 2900; 48% white, 28% black, 7% Hispanic, 8% Chinese, 9% Japanese) participating in SWAN over 7 years with repeated assessments of CV risk factors.
Consumption of wine was stable and common with 20% reporting none, 69% light (<1/day), 7% moderate ( = 1/day), and 4% heavy (>1/day).
To guard against underreporting, reseachers took the maximum reported wine consumption over 7 years as the predictor. They used mixed models with a random intercept and random time to assess the relationship between wine consumption and CV risk factors with moderate consumption as the reference. Outcome variables were log-transformed where necessary. Longitudinal models were adjusted for ethnicity, age, and time-varying menopausal status, hormone therapy use, overall alcohol consumption, high density lipoprotein (HDL), statin use, and a healthy lifestyle score based on physical activity, not smoking, and weight maintenance.
Interactions of wine consumption with time were not significant.
Moderate wine consumers had significantly lower levels of C-reactive protein (CRP, p < .001), fibrinogen (p < .001), factor VII (p < .01), and plasminogen activator inhibitor (PAI-1, p < .05) than women who drank no or little wine.
These associations were independent of significant effects of healthy lifestyle and overall alcohol consumption and similar across ethnic groups. Moderate wine consumption may protect against CVD via inflammatory and clotting pathways.
So, epidemiological evidence suggests an inverse correlation between wine consumption and the incidence of cardiovascular and neurodegenerative disorders.
Although white wines are generally low in polyphenol content as compared to red wines, Champagne wine has been shown to contain relatively high amounts of phenolic acids that may exert protective cellular actions in vivo.
Recent evidence suggest that Champagne phenolic acids may express their beneficial properties through their interaction with cellular signaling pathways and related machinery that mediate cell function under both normal and pathological conditions.
In this review we aim to provide an overview of the role that Champagne consumption plays in maintaining cardiovascular health and cognitive function. We discuss epidemiological data, human intervention study findings, as well as animal and in vitro studies in support of these actions and we consider how their biological mechanisms at the cellular level may underpin their physiological effects.
Together, these data indicate that polyphenols present in Champagne may hold cardioprotective and neuroprotective potential in delaying the onset of degenerative disorders.
by R. T.
30 june 2014, Technical Area > Grapevine & Wine